Instituto de Biociências Universidade de São Paulo
LPBR

Publicações em periódicos

  •   Kumar, A., Furtado, V. L., Gonçalves, J.M., Bannitz-Fernandes, R., Netto, L.E. S., Araki, K., Bertotti, M. Amperometric microsensor based on nanoporus gold for ascorbic acid in highly acidic biological extracts.2020 Jan 25; 1095:61-70.doi:10.1016/j.aca.2019.10.022
  •  Leme, J. M.M., Ohara, E., Santiago, V.F., Barros, M.H., Netto, L.E.S., Pimenta, D. C., Mariano, D.O.C., Oliveira, C.L.P., Bicev, R.N., Barreto-Chaves, M.L.M., Lino, C.A.,Demasi, M. Mutations of Cys and Ser residues in the α5-subunit of the 20S proteasome from Sacharomyces cerevisiae affects gating and chronological lifespan. Arch Biochem Biophys 2019 May15, 666: 63-72. Doi:10/1016/j.abb.2019.03.012
  •  Truzzi, D. R., Coelho, F. R., Paviani, V., Alves, S. V., Netto, L.E.S., Augusto, O.The bicarbonate/carbon dioxide pair increases hydrogen-peroxide mediated hyperoxidation of human peroxiredoxin 1J Biol Chem. 2019 Sep 20, 294(38):14055-14067. doi:10.1074/jbc.RA119.008825.
  • Gimenez M, Veríssimo-Filho S, Wittig I, Schickling BM, Hahner F, Schürmann C, Netto LES, Rosa JC, Brandes RP, Sartoretto S, De Lucca Camargo L, Abdulkader F, Miller FJ Jr, Lopes LR. Redox Activation of Nox1 (NADPH Oxidase 1) Involves an Intermolecular Disulfide Bond Between Protein Disulfide Isomerase and p47phox in Vascular Smooth Muscle Cells.Arterioscler Thromb Vasc Biol. 2019 Feb;39(2):224-236. doi: 10.1161/ATVBAHA.118.311038.

  • Chaves NA, Alegria TGP, Dantas LS, Netto LES, Miyamoto S, Bonini Domingos CR, da Silva DGH. Impaired antioxidant capacity causes a disruption of metabolic homeostasis in sickle erythrocytes.Free Radic Biol Med. 2019 Jun 1. pii: S0891-5849(19)30505-2. doi: 10.1016/j.freeradbiomed.2019.05.034.

  • Melo KP, Silva CM, Almeida MF, Chaves RS, Marcourakis T, Cardoso SM, Demasi M, Netto LES, Ferrari MFR. Mild Exercise Differently Affects Proteostasis and Oxidative Stress on Motor Areas During Neurodegeneration: A Comparative Study of Three Treadmill Running Protocols.Neurotox Res. 2019 Feb;35(2):410-420. doi: 10.1007/s12640-018-9966-3. Epub 2018 Oct 1.

  • DE ARMAS, MARÍA INÉS ; ESTEVES, ROMINA ; VIERA, NICOLÁS ; REYES, ANÍBAL M. ; MASTROGIOVANNI, MAURICIO ; ALEGRIA, THIAGO G.P. ; Netto, Luis E.S. ; TÓRTORA, VERÓNICA ; Radi, Rafael ; Trujillo, Madia . Rapid peroxynitrite reduction by human peroxiredoxin 3: Implications for the fate of oxidants in mitochondria. FREE RADICAL BIOLOGY AND MEDICINE, v. 130, p. 369-378, 2019.

  • BANNITZ-FERNANDES, RENATA ; ALEIXO-SILVA, ROGÉRIO ; SILVA, JOÃO ; DODIA, CHANDRA ; VAZQUEZ-MEDINA, JOSE ; TAO, JIAN-QIN ; FISHER, ARON ; Netto, Luis . Non-Mammalian Prdx6 Enzymes (Proteins with 1-Cys Prdx Mechanism) Display PLA2 Activity Similar to the Human Orthologue. ANTIOXIDANTS, v. 8, p. 52, 2019.

  • LEME, JANAÍNA M.M. ; OHARA, ERINA ; SANTIAGO, VERÔNICA F. ; BARROS, MARIO H. ; Netto, Luis E.S. ; PIMENTA, DANIEL C. ; MARIANO, DOUGLAS O.C. ; OLIVEIRA, CRISTIANO L.P. ; BICEV, RENATA N. ; DE CHAVES, MARIA L.M. B. ; LINO, CAROLINE A. ; DEMASI, Marilene . Mutations of Cys and Ser residues in the α5-subunit of the 20S proteasome from Saccharomyces cerevisiae affects gating and chronological lifespan. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, v. 666, p. 63-72, 2019

  • SANTOS, CARLA S. ; BANNITZ-FERNANDES, RENATA ; LIMA, ALEX S. ; TAIRUM, CARLOS A. ; MALAVAZI, IRAN ; NETTO, LUIS EDUARDO S. ; BERTOTTI, MAURO . Monitoring H 2 O2 inside Aspergillus fumigatus with an integrated microelectrode: the role of peroxiredoxin protein Prx1. ANALYTICAL CHEMISTRY, v. 90, p. 2587-2593, 2018.

  • PICCIRILLO, ERIKA ; ALEGRIA, THIAGO G. P. ; DISCOLA, KAREN F. ; CUSSIOL, JOSÉ R. R. ; DOMINGOS, RENATO M. ; DE OLIVEIRA, MARCOS A. ; REZENDE, LEANDRO DE ; Netto, Luis E. S. ; AMARAL, ANTONIA T-DO . Structural insights on the efficient catalysis of hydroperoxide reduction by Ohr: Crystallographic and molecular dynamics approaches. PLoS One, v. 13, p. e0196918, 2018.

  • ROCHA, MARINA CAMPOS ; DE GODOY, KRISSIA FRANCO ; BANNITZ-FERNANDES, RENATA ; FABRI, JOÃO H. T. MARILHANO ; BARBOSA, MAYRA M. FERRARI ; DE CASTRO, PATRÍCIA ALVES ; ALMEIDA, FAUSTO ; GOLDMAN, GUSTAVO HENRIQUE ; DA CUNHA, ANDERSON FERREIRA ; Netto, Luis E. S. ; DE OLIVEIRA, MARCOS ANTONIO ; MALAVAZI, IRAN . Analyses of the three 1-Cys Peroxiredoxins from Aspergillus fumigatus reveal that cytosolic Prx1 is central to H2O2 metabolism and virulence. Scientific Reports, v. 8, p. 12314, 2018.

  • ROMANELLO, KAREN S. ; TEIXEIRA, KARINA K. L. ; SILVA, JOÃO PEDRO M. O. ; NAGAMATSU, SHEILA T. ; BEZERRA, MARCOS ANDRÉ C. ; DOMINGOS, IGOR F. ; MARTINS, DIEGO A. P. ; ARAUJO, ADERSON S. ; LANARO, CAROLINA ; BREYER, CARLOS A. ; FERREIRA, REGIANE A. ; FRANCO-PENTEADO, CARLA ; COSTA, FERNANDO F. ; MALAVAZI, IRAN ; Netto, Luis E. S. ; DE OLIVEIRA, MARCOS A. ; CUNHA, ANDERSON F. . Global analysis of erythroid cells redox status reveals the involvement of Prdx1 and Prdx2 in the severity of beta thalassemia. PLoS One, v. 13, p. e0208316, 2018.

  • MELO, KARLA P. ; SILVA, CAROLLINY M. ; ALMEIDA, MICHAEL F. ; CHAVES, RODRIGO S. ; MARCOURAKIS, TANIA ; CARDOSO, SANDRA M. ; DEMASI, Marilene ; Netto, Luis E. S. ; FERRARI, MERARI F. R. . Mild Exercise Differently Affects Proteostasis and Oxidative Stress on Motor Areas During Neurodegeneration: A Comparative Study of Three Treadmill Running Protocols. NEUROTOXICITY RESEARCH, v. 35, p. 410-420, 2018.

  • TURANO, H. ; GOMES, F. ; BARROS-CARVALHO, G. ; LOPES, R. ; CERDEIRA, L. ; Netto, LES ; GALES, A. ; LINCOPAN, N. . Tn 6350 , a Novel Transposon Carrying Pyocin S8 Genes Encoding a Bacteriocin with Activity against Carbapenemase-Producing Pseudomonas aeruginosa. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, v. 61, p. e00100-17, 2017.

  • MORAIS, MARIANA A. B. ; GIUSEPPE, PRISCILA O. ; SOUZA, TATIANA A. C. B. ; CASTRO, HELENA ; HONORATO, RODRIGO V. ; OLIVEIRA, PAULO S. L. ; Netto, Luis E. S. ; TOMAS, ANA M. ; MURAKAMI, MARIO T. . Calcium and Magnesium Ions Modulate the Oligomeric State and Function of Mitochondrial 2-Cys Peroxiredoxins in Leishmania Parasites. JOURNAL OF BIOLOGICAL CHEMISTRY, v. 292, p. jbc.M116.762039-7039, 2017.

  • CARVALHO, LARISSA A. C. ; TRUZZI, DANIELA R. ; FALLANI, THAMIRIS S. ; ALVES, SIMONE V. ; TOLEDO JUNIOR, JOSE CARLOS ; AUGUSTO, Ohara ; Netto, Luis E. S. ; MEOTTI, FLAVIA C. . Urate hydroperoxide oxidizes human peroxiredoxin 1 and peroxiredoxin 2. JOURNAL OF BIOLOGICAL CHEMISTRY, v. 292, p. jbc.M116.767657-8715, 2017.

  • MEIRELES, D.A. ; DOMINGOS, R.M. ; GAIARSA, J.W. ; RAGNONI, E.G. ; BANNITZ-FERNANDES, R. ; DA SILVA NETO, J.F. ; DE SOUZA, R.F. ; Netto, L.E.S. . Functional and evolutionary characterization of Ohr proteins in eukaryotes reveals many active homologs among pathogenic fungi. Redox Biology, v. 12, p. 600-609, 2017.

  • PREVIATO MELLO, MARISTELA ; MEIRELES, DIOGO DE ABREU ; Netto, Luis Eduardo Soares ; DA SILVA NETO, JOSÉ FREIRE . The global transcriptional response to organic hydroperoxide and the role of OhrR in the control of virulence traits in Chromobacterium violaceum. INFECTION AND IMMUNITY, v. 85, p. IAI.00017-17, 2017.

  • GOMES, FERNANDO ; PALMA, FLAVIO ROMERO ; BARROS, MARIO H. ; TSUCHIDA, EDUARDO T. ; TURANO, HELENA G. ; ALEGRIA, THIAGO G. P. ; DEMASI, Marilene ; Netto, Luis E. S. . Proteolytic cleavage by the IMP complex or Oct1 peptidase controls the localization of the yeast peroxiredoxin Prx1 to distinct mitochondrial compartments. JOURNAL OF BIOLOGICAL CHEMISTRY, v. 292, p. 17011-17024, 2017.

  • ALMEIDA, M. F. ; SILVA, C. M. ; CHAVES, R. S. ; LIMA, N. C. R. ; ALMEIDA, R. S. ; MELO, K. P. ; DEMASI, M. ; FERNANDES, T. ; OLIVEIRA, E. M. ; Netto, Luis E.S. ; CARDOSO, S. M. ; FERRARI, M. F. R. . Effects of mild running on substantia nigra during early neurodegeneration. JOURNAL OF SPORTS SCIENCES, v. 1, p. 1-8, 2017.

  • Netto, Luis E. S.; DE OLIVEIRA, MARCOS ANTONIO ; TAIRUM-JR, CARLOS ; DA SILVA NETO, JOSÉ FREIRE . Conferring specificity in redox pathways by enzymatic thiol/disulfide exchange reactions. Free Radical Research, v. 50, p. 206-245, 2016.

  • Netto LE; ANTUNES, F. . The Roles of Peroxiredoxin and Thioredoxin in Hydrogen Peroxide Sensing and in Signal Transduction. MOLECULES AND CELLS, v. 39, p. 65-71, 2016.

  • TAIRUM, CARLOS A. ; SANTOS, MELINA CARDOSO ; BREYER, CARLOS A. ; GEYER, R. RYAN ; NIEVES, CECILIA J. ; PORTILLO-LEDESMA, STEPHANIE ; FERRER-SUETA, GERARDO ; Toledo, José Carlos ; TOYAMA, MARCOS H. ; AUGUSTO, Ohara ; Netto, Luis E. S. ; DE OLIVEIRA, MARCOS A. . Catalytic Thr or Ser Residue Modulates Structural Switches in 2-Cys Peroxiredoxin by Distinct Mechanisms. Scientific Reports, v. 6, p. 33133, 2016.

  • ALEGRIA, THIAGO G. P. ; MEIRELES, DIOGO A. ; CUSSIOL, JOSÉ R. R. ; HUGO, MARTÍN ; Trujillo, Madia ; DE OLIVEIRA, MARCOS ANTONIO ; MIYAMOTO, SAYURI ; QUEIROZ, RAPHAEL F. ; VALADARES, NAPOLEÃO FONSECA ; GARRATT, RICHARD C. ; Radi, Rafael ; DI MASCIO, PAOLO ; AUGUSTO, Ohara ; Netto, Luis E. S. . Ohr plays a central role in bacterial responses against fatty acid hydroperoxides and peroxynitrite. Proceedings of the National Academy of Sciences of the United States of America, v. 114, p. 201619659, 2016.

  • MORAIS, M. A. ; GIUSEPPE, P. O. ; SOUZA, T. A. ; Alegria, T. G. P. ; OLIVEIRA, M. A. ; Netto, Luis Eduardo Soares ; MURAKAMI, M. T. . How pH Modulates the Dimer-Decamer Interconversion of 2-Cys peroxiredoxins from the Prx1 subfamily. The Journal of Biological Chemistry (Print), v. 290, p. 8582-8590, 2015.

 

  •  APPOLINARIO, P. P. ; Medinas D ; CHAVES-FILHO, A. B. ; GENARO-MATTOS, T. C. ; QUEIROZ, R. ; Cussiol, J. R. R. ; Netto, Luis E.S ; AUGUSTO, Ohara ; MIYAMOTO, S. . Oligomerization of Cu,Zn-Superoxide Dismutase (SOD1) by Docosahexaenoic Acid and Its Hydroperoxides In Vitro: Aggregation Dependence on Fatty Acid Unsaturation and Thiols. Plos One, v. 10, p. e0125146, 2015.

  • DEMASI, Marilene ; HAND, ADRIAN ; OLIVEIRA, CRISTIANO L.P. ; BICEV, RENATA N. ; BERTONCINI, CLELIA A. ; Netto, Luis E.S. . 20S Proteasome Activity is Modified via S-glutathionylation Based on Intracellular Redox Status of the Yeast Saccharomyces Cerevisiae: Implications for the Degradation of Oxidized Proteins. Archives of Biochemistry and Biophysics (Print), v. 1, p. 1-10, 2014.

  • KAIHAMI, G. H. ; Almeida, JRF ; SANTOS, S. S. ; Netto, Luis E.S. ; ALMEIDA, S. R. ; Baldini RL . Involvement of a 1-Cys Peroxiredoxin in Bacterial Virulence. PLoS Pathogens (Online), v. 10, p. e1004442, 2014.

  • LEMKE, LAURA SIMONI ; CHURA-CHAMBI, ROSA MARIA ; RODRIGUES, DANIELLA ; CUSSIOL, JOSE RENATO ROSA ; NATALIA VALLEJO ; ALEGRIA, THIAGO GERONIMO PIRES ; Netto, Luis Eduardo Soares ; MORGANTI, LIGIA . Investigation on solubilization protocols in the refolding of the thioredoxin TsnC from Xylella fastidiosa by high hydrostatic pressure approach. Protein Expression and Purification (Print), v. 106, p. 72-77, 2014.

  • MEIRELES, DIOGO DE ABREU ; ALEGRIA, THIAGO GERONIMO PIRES ; ALVES, S. V. ; ARANTES, CARLA RANI ROCHA ; NETTO, LE . A 14.7 kDa Protein from Francisella tularensis subsp. novicida (Named FTN_1133), Involved in the Response to Oxidative Stress Induced by Organic Peroxides, Is Not Endowed with Thiol-Dependent Peroxidase Activity. Plos One, v. 9, p. e99492, 2014.

  • MORETTI-ALMEIDA, GABRIEL ; NETTO, LE ; MONTEIRO, G. . The essential gene YMR134W from Saccharomyces cerevisiae is important for appropriate mitochondrial iron utilization and the ergosterol biosynthetic pathway. FEBS Letters (Print), v. 587, p. 3008-3013, 2013.

  • SILVA, Gustavo Monteiro da ; Netto, Luis Eduardo Soares ; SIMOES, V. ; SANTOS, L. ; GOZZO, F. C. ; Demasi MAA ;M.C ; DEMASI, Marilene . Redox Control of 20S Proteasome Gating. Antioxidants & Redox Signalling, v. 16, p. 1183-1194, 2012
  • TAIRUM-JR, C. A. ; OLIVEIRA, M. A. ; HORTA, Bruno Brasil ; Zara, FJ ; NETTO, L. E. S. . Disulfide Biochemistry in 2-Cys Peroxiredoxin: Requirement of Glu50 and Arg146 for the Reduction of Yeast Tsa1 by Thioredoxin. Journal of Molecular Biology, v. 424, p. 28-41, 2012.

  • Da Silva Neto, José. F. ; Negretto, Caroline C. ; Netto, Luis E. S. . Analysis of the Organic Hydroperoxide Response of Chromobacterium violaceum Reveals That OhrR Is a Cys-Based Redox Sensor Regulated by Thioredoxin. Plos One, v. 7, p. e47090, 2012.

  • Netto CG, Nakamatsu EH, Netto LE, Novak MA, Zuin A, Nakamura M, Araki K, Toma HE. Catalytic properties of thioredoxin immobilized on superparamagnetic nanoparticles. J Inorg Biochem. 2011 May;105(5):738-44. 
  • Toledo JC Jr, Audi R, Ogusucu R, Monteiro G, Netto LE, Augusto O. Horseradish peroxidase compound I as a tool to investigate reactive protein-cysteine residues: from quantification to kinetics.Free Radic Biol Med. 2011 May 1;50(9):1032-8. 
  • Sartorello R, Budu A, Bagnaresi P, Fernandes CA, Sato PM, Bueno VB, Fontes MR, Oliveira PL, Paiva-Silva GO, Alves SV, Netto LE, Catalani LH, Garcia CR. In vivo uptake of a haem analogue Zn protoporphyrin IX by the human malaria parasite P. falciparum-infected red blood cells. Cell Biol Int. 2010 Aug 1;34(8):859-65.
  • Cussiol JR, Alegria TG, Szweda LI, Netto LE. Ohr (organic hydroperoxide resistance protein) possesses a previously undescribed activity, lipoyl-dependent peroxidase. J Biol Chem. 2010 Jul 16;285(29):21943-50. 
  • Horta BB, de Oliveira MA, Discola KF, Cussiol JR, Netto LE.Structural and biochemical characterization of peroxiredoxin Qbeta from Xylella fastidiosa: catalytic mechanism and high reactivity. J Biol Chem. 2010 May 21;285(21):16051-65. Epub 2010 Mar 24.
  • Oliveira MA, Discola KF, Alves SV, Medrano FJ, Guimarães BG, Netto LE Insights into the specificity of thioredoxin reductase-thioredoxin interactions. A structural and functional investigation of the yeast thioredoxin system. Biochemistry. 2010 Apr 20;49(15):3317-26.
  • Hugo M, Turell L, Manta B, Botti H, Monteiro G, Netto LE, Alvarez B, Radi R, Trujillo M. Thiol and sulfenic acid oxidation of AhpE, the one-cysteine peroxiredoxin from Mycobacterium tuberculosis: kinetics, acidity constants, and conformational dynamics. Biochemistry. 2009 Oct 13;48(40):9416-26.
  • Ogusucu R, Rettori D, Netto LE, Augusto O. Superoxide dismutase 1-mediated production of ethanol- and DNA-derived radicals in yeasts challenged with hydrogen peroxide: molecular insights into the genome instability of peroxiredoxin-null strains. J Biol Chem. 2009 Feb 27;284(9):5546-56. 
  • Discola KF, de Oliveira MA, Rosa Cussiol JR, Monteiro G, Bárcena JA, Porras P, Padilla CA, Guimarães BG, Netto LE. Structural aspects of the distinct biochemical properties of glutaredoxin 1 and glutaredoxin 2 from Saccharomyces cerevisiae. J Mol Biol. 2009 Jan 23;385(3):889-901. 
  • Silva GM, Netto LE, Discola KF, Piassa-Filho GM, Pimenta DC, Bárcena JA, Demasi M. Role of glutaredoxin 2 and cytosolic thioredoxins in cysteinyl-based redox modification of the 20S proteasome. FEBS J. 2008 Jun;275(11):2942-55. Epub 2008 Apr 23.
  • Pinheiro AS, Amorim GC, Netto LE, Almeida FC, Valente AP. NMR solution structure of the reduced form of thioredoxin 1 from Sacharomyces cerevisiae. Proteins. 2008 Feb 1;70(2):584-7. 
  • Oliveira MA, Genu V, Discola KF, Alves SV, Netto LE, Guimarães BG. Crystallization and preliminary X-ray analysis of a decameric form of cytosolic thioredoxin peroxidase 1 (Tsa1), C47S mutant, from Saccharomyces cerevisiae. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Aug 1;63(Pt 8):665-8. 
  • Monteiro G, Horta BB, Pimenta DC, Augusto O, Netto LE. Reduction of 1-Cys peroxiredoxins by ascorbate changes the thiol-specific antioxidant paradigm, revealing another function of vitamin C. Proc Natl Acad Sci U S A. 2007 Mar 20;104(12):4886-91. Epub 2007 Mar 14.
  • Amorim GC, Pinheiro AS, Netto LE, Valente AP, Almeida FC. NMR solution structure of the reduced form of thioredoxin 2 from Saccharomyces cerevisiae. J Biomol NMR. 2007 May;38(1):99-104. 
  • Ogusucu R, Rettori D, Munhoz DC, Netto LE, Augusto O. Reactions of yeast thioredoxin peroxidases I and II with hydrogen peroxide and peroxynitrite: rate constants by competitive kinetics. Free Radic Biol Med. 2007 Feb 1;42(3):326-34. 
  • Tahara EB, Barros MH, Oliveira GA, Netto LE, Kowaltowski AJ.Dihydrolipoyl dehydrogenase as a source of reactive oxygen species inhibited by caloric restriction and involved in Saccharomyces cerevisiae aging. FASEB J. 2007 Jan;21(1):274-83. 
  • Netto LE, de Oliveira MA, Monteiro G, Demasi AP, Cussiol JR, Discola KF, Demasi M, Silva GM, Alves SV, Faria VG, Horta BB. Reactive cysteine in proteins: protein folding, antioxidant defense, redox signaling and more. Comp Biochem Physiol C Toxicol Pharmacol. 2007 Jul-Aug;146(1-2):180-93. Epub 2006 Sep 6. Review.
  • Barbosa JA, Netto LE, Farah CS, Schenkman S, Meneghini R. The structural molecular biology network of the State of São Paulo, Brazil. An Acad Bras Cienc. 2006 Jun;78(2):241-53. 
  • Oliveira MA, Guimarães BG, Cussiol JR, Medrano FJ, Gozzo FC, Netto LE.Structural insights into enzyme-substrate interaction and characterization of enzymatic intermediates of organic hydroperoxide resistance protein from Xylella fastidiosa. J Mol Biol. 2006 Jun 2;359(2):433-45.
  • Pinheiro AS, Amorim GC, Netto LE, Valente AP, Almeida FC. 1H, 13C and 15N resonance assignments for the reduced forms of thioredoxin 1 and 2 from S. cerevisiae. J Biomol NMR. 2006;36 Suppl 1:35. 
  • Discola KF, Oliveira MA, Silva GM, Barcena JA, Porras P, Padilla A, Netto LE, Guimarães BG. Crystallization and preliminary X-ray crystallographic studies of glutaredoxin 2 from Saccharomyces cerevisiae in different oxidation states. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 Apr 1;61(Pt 4):445-7. 
  • Oliveira MA, Discola KF, Alves SV, Barbosa JA, Medrano FJ, Netto LE, Guimarães BG. Crystallization and preliminary X-ray diffraction analysis of NADPH-dependent thioredoxin reductase I from Saccharomyces cerevisiae. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 Apr 1;61(Pt 4):387-90. 
  • Demasi AP, Pereira GA, Netto LE.Yeast oxidative stress response. Influences of cytosolic thioredoxin peroxidase I and of the mitochondrial functional state. FEBS J. 2006 Feb;273(4):805-16.
  • Medina-Silva R, Barros MP, Galhardo RS, Netto LE, Colepicolo P, Menck CF. Heat stress promotes mitochondrial instability and oxidative responses in yeast deficient in thiazole biosynthesis. Res Microbiol. 2006 Apr;157(3):275-81. 
  • Monteiro G, Netto LE.Glucose repression of PRX1 expression is mediated by Tor1p and Ras2p through inhibition of Msn2/4p in Saccharomyces cerevisiae.FEMS Microbiol Lett. 2004 Dec 15;241(2):221-8.
  • Munhoz DC, Netto LE.Cytosolic thioredoxin peroxidase I and II are important defenses of yeast against organic hydroperoxide insult: catalases and peroxiredoxins cooperate in the decomposition of H2O2 by yeast. J Biol Chem. 2004 Aug 20;279(34):35219-27. 
  • Monteiro G, Kowaltowski AJ, Barros MH, Netto LE.Glutathione and thioredoxin peroxidases mediate susceptibility of yeast mitochondria to Ca(2+)-induced damage. Arch Biochem Biophys. 2004 May 1;425(1):14-24.
  • Oliveira MA, Netto LE, Medrano FJ, Barbosa JA, Alves SV, Cussiol JR, Guimarães BG.Crystallization and preliminary X-ray diffraction analysis of an oxidized state of Ohr from Xylella fastidiosa. Acta Crystallogr D Biol Crystallogr. 2004 Feb;60(Pt 2):337-9
  • Barros MH, Netto LE, Kowaltowski AJ. H(2)O(2) generation in Saccharomyces cerevisiae respiratory pet mutants: effect of cytochrome c. Free Radic Biol Med. 2003 Jul 15;35(2):179-88.
  • Boschero AC, Stoppiglia LF, Collares-Buzato CB, Bosqueiro JR, Delghingaro-Augusto V, Leite A, Carvalho CP, Netto LE, Carneiro EM. Expression of a thioredoxin peroxidase in insulin-producing cells. Diabetes Metab. 2002 Dec;28(6 Pt 2):3S25-8; discussion 3S108-12.
  • Cussiol JR, Alves SV, de Oliveira MA, Netto LE. Organic hydroperoxide resistance gene encodes a thiol-dependent peroxidase. J Biol Chem. 2003 Mar 28;278(13):11570-8. 
  • Demasi M, Silva GM, Netto LE. 20 S proteasome from Saccharomyces cerevisiae is responsive to redox modifications and is S-glutathionylated. J Biol Chem. 2003 Jan 3;278(1):679-85. 
  • Netto LE, Kowaltowski AJ, Castilho RF, Vercesi AE. Thiol enzymes protecting mitochondria against oxidative damage. Methods Enzymol. 2002;348:260-70. 
  • Monteiro G, Pereira GA, Netto LE.Regulation of mitochondrial thioredoxin peroxidase I expression by two different pathways: one dependent on cAMP and the other on heme. Free Radic Biol Med. 2002 Feb 1;32(3):278-88.
  • Demasi AP, Pereira GA, Netto LE.Cytosolic thioredoxin peroxidase I is essential for the antioxidant defense of yeast with dysfunctional mitochondria. FEBS Lett. 2001 Dec 14;509(3):430-4.
  • Almeida FC, Amorim GC, Moreau VH, Sousa VO, Creazola AT, Américo TA, Pais AP, Leite A, Netto LE, Giordano RJ, Valente AP. Selectively labeling the heterologous protein in Escherichia coli for NMR studies: a strategy to speed up NMR spectroscopy. J Magn Reson. 2001 Jan;148(1):142-6.
  • Netto, LE . Regulation of antioxidant defenses. Antioxidants And Life Style, Argentine, 2001. http://www.antioxidantes.com.ar/Art129.htm
  • Netto, LE . Oxidative Stress Response in Sugarcane. Genetics and Molecular Biology, v. 24, n. 1-4, p. 93-102, 2001.
  • Simpson AJ et al. The genome sequence of the plant pathogen Xylella fastidiosa. The Xylella fastidiosa Consortium of the Organization for Nucleotide Sequencing and Analysis. Nature. 2000 Jul 13;406(6792):151-9.
  • Kowaltowski AJ, Vercesi AE, Rhee SG, Netto LE.Catalases and thioredoxin peroxidase protect Saccharomyces cerevisiae against Ca(2+)-induced mitochondrial membrane permeabilization and cell death. FEBS Lett. 2000 May 12;473(2):177-82.
  • Rhee SG, Kang SW, Netto LE, Seo MS, Stadtman ER. A family of novel peroxidases, peroxiredoxins. Biofactors. 1999;10(2-3):207-9. Review. 
  • Kowaltowski AJ, Netto LE, Vercesi AE. The thiol-specific antioxidant enzyme prevents mitochondrial permeability transition. Evidence for the participation of reactive oxygen species in this mechanism. J Biol Chem. 1998 May 22;273(21):12766-9.
  • Netto LE, Stadtman ER. The iron-catalyzed oxidation of dithiothreitol is a biphasic process: hydrogen peroxide is involved in the initiation of a free radical chain of reactions. Arch Biochem Biophys. 1996 Sep 1;333(1):233-42.
  • Netto, LE ; Chae, H. Z. ; Kang SW ; Rhee, S. G. ; Stadtman, E. R. . Removal Of Hydrogen Peroxide By Thiol Specific Antioxidant (Tsa) Is Involved With Its Antioxidant Properties. Tsa Possess Thiol Peroxidase Activity. J. Biol. Chem, 1996 271(26): 15315-15321.
  • Rhee SG, Kim KH, Chae HZ, Yim MB, Uchida K, Netto LE, Stadtman ER. Antioxidant defense mechanisms: a new thiol-specific antioxidant enzyme. Ann N Y Acad Sci. 1994 Nov 17;738:86-92. Review. 
  • Netto LE, RamaKrishna NV, Kolar C, Cavalieri EL, Rogan EG, Lawson TA, Augusto O. Identification of C8-methylguanine in the hydrolysates of DNA from rats administered 1,2-dimethylhydrazine. Evidence for in vivo DNA alkylation by methyl radicals. J Biol Chem. 1992 Oct 25;267(30):21524-7.
  • Augusto O, Netto LE, Gomes LF.DNA alkylation by carbon-centered radicals. Braz J Med Biol Res. 1992;25(12):1171-83. Review.
  • Netto LE, Ferreira AM, Augusto O.Iron(III) binding in DNA solutions: complex formation and catalytic activity in the oxidation of hydrazine derivatives. Chem Biol Interact. 1991;79(1):1-14.
  • Netto LE, Leite LC, Augusto O. Hemoglobin-mediated oxidation of the carcinogen 1,2-dimethylhydrazine to methyl radicals. Arch Biochem Biophys. 1988 Nov 1;266(2):562-72.
  • Netto LE, Leite LC, Augusto O. Enzymatic activation of the carcinogens 2-phenylethylhydrazine and 1,2-dimethylhydrazine to carbon-centered radicals. Braz J Med Biol Res. 1987;20(6):865-8.

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